Chunming Dong CV

Chunming Dong Associate Professor

Department of Marine Science

Phone: 18222285630

Location: Rm510 Building No.6

E-mail：mingchundongjy@tust.edu.cn

Research Interests

Construction of genetic engineering strains for efficient expression of active protein peptides of marine biomass, optimisation of protein expression and purification processes, evaluation of efficacy, constitutive relationships and industrialisation applications.

Academic Advising

Now accepting masters candidates in Marine Science and Resources and Environment.

Education（in reverse chronological order）

Ph.D. in of Science, Nankai University, 2011-2016

Bachelor of Science, Shandong First Medical University, 2007-2011

Positions & Employment（in reverse chronological order）

2024-present College of Marine and Environmental Science, Tianjin University of Science and Technology, Associate Professor

2017-2023 College of Marine and Environmental Science, Tianjin University of Science and Technology, Research Associate

Teaching

For Undergraduates: Utilization of Marine biological resources, biological separation engineering, and biochemistry experiments

Research Projects（in reverse chronological order）

1） National Science Foundation for Youth: Research on the structure and function of human ASXL 2 and ASXL 2-BAP 1 complexes, has been completed;

2） Project of Tianjin Municipal Education Commission: Research on the structure, molecular improvement and antibacterial mechanism of the new defensin Acipensins1, in research;

3） Horizontal topic: Strain construction, expression, purification and performance study of recombinant human-derived collagen, plant insulin Aglycin and Vglycin, in research;

4） Horizontal topic: New alcocyanine protein product research and development and purification process optimization, in research;

5） Horizontal topic: Screening, expression, purification and performance study of recombinant human type III collagen, in research;

6） Horizontal topic: strain construction, activity determination and application research of efficient expression of TA1, Sc and other antimicrobial peptides, in research;

7） Horizontal topic: Molecular construction, expression, purification and performance study of allergen recombinant protein, in research;

8） Horizontal topic: Construction and screening of Novel Coronavirus S protein nanoantibody library, in research;

9） Horizontal topic: Construction and screening of Flag / GFP tag nano antibody library,, has been concluded.

Key Publications：（*corresponding author, in reverse chronological order）

1） Chunming Dong,Lijun Xu,Weitao Lu,Mengru Li,Rui Zhang,Yanyan Sun,Jian Liu,Xinlei Chu. Antibacterial peptide PMAP-37(F34-R), expressed in Pichia pastoris, is effective against pathogenic bacteria and preserves plums. Microb Cell Fact. 2023 Aug 27;22(1):164. (IF:6.399)

2） Chunming Dong, Mengru Li, Rui Zhang, Weitao Lu,Lijun Xu,Jian Liu,Xinlei Chu. The Expression of Antibacterial Peptide Turgencin A in Pichia pastoris and an Analysis of Its Antibacterial Activity. Molecules. 2023 Jul 14;28(14):5405. (IF:4.600)

3） Chunming Dong, Guihong Zhao, Lei Tao, Fanghang Qiu, Shujing Wang, Bo Wang, Jian Liu, Shengxia Duan. Antioxidant Interactions between S-allyl-L-cysteine and Polyphenols Using Interaction Index and Isobolographic Analysis. Molecules. 2022;27(13):4089. (IF:4.600)

4） Chunming Dong, Rui Zhang, Lijun Xu, Beibei Liu, Xinlei Chu. Assembly and interaction of core subunits of BAF complexes and crystal study of the SMARCC1/SMARCE1 binary complex. Biochem Biophys Res Commun. 2022 Apr 9;599:9-16.

5） Bin Xue, Chunming Dong, Hehe Hu, Bin Dong, Zhenchuan Fan. Chlamydomonas reinhardtii-expressed Multimer of ToAMP4 Inhibits the Growth of Bacteria of both Gram-positive and Gram-negative[J]. Process Biochemistry, 2020, 91:311-318.

6） Hao Zhou, Guidong Chen, Chunming Dong, Xiaozhou Zhao, Zhongtian Shen, Feilong Chen, Beibei Liu, Jiafu Long. Snf5 and Swi3 subcomplex formation is required for SWI/SNF complex function in yeast. Biochem Biophys Res Commun. 2020 Jun 11;526(4):934-940.

7） Mengru Li, Lijun Xu, Rui Zhang, Chunming Dong*. Epigenetic Regulator ASXL2: Structure, Function and its Predictive Value in Diseases. Curr Protein Pept Sci. 2023;24(1):22-30.

8） Mengru Li, Weitao Lu, Yanyan Sun, Chunming Dong*. Antimicrobial Peptides: Sources, Expression Systems, and Applications. Curr Protein Pept Sci. 2023;10.2174/1389203724666230727101636.

9） Weitao Lu, Mengru Li, Yibo Yang, Yanyan Sun, Chunming Dong*. Research progress of BAP1 in structure, function and cancer. Protein Pept Lett. 2023;30(7):552-561.

10） Rui Zhang, Lijun Xu, Chunming Dong*. Antimicrobial peptides: an overview of their structure, function and mechanism of action. Protein Pept Lett. 2022 Jun 13.