Team Leader and Academic Title:
Song Donghui, Professor (Ph.D., Zhejiang University)
Team Members and Their Academic Titles:
Liu Hongyan, Professor(Ph.D., Chinese Academy of Sciences. Distinguished Teacher of Ideological and Political Education in Tianjin's Higher Education Institutions)
Dong Chunming, Associate Professor(Ph.D., Nankai University. Young Talent in the Discipline of Tianjin's Higher Education Institutions)
Team Introduction (Highlighting Research Directions):
The primary research directions of our team include:
Research on the Biodegradation Mechanisms of Marine Persistent Pollutants
Management of Marine Heavy Metal Pollution and Research on Microalgal Bioenergy
Research on Antimicrobial Peptides and High-Efficiency Expressing Protease Strains
Research on the Drivers and Mechanisms of Carbon Sequestration in Coastal Wetlands
Based on the regulatory mechanisms of microbiomics, transcriptomics, proteomics and metabolomics, the team uses molecular biology techniques, bioinformatics and modern bioengineering technologies as means to continuously develop new technologies such as multiple microbial degradation functional flora, energy seaweeds, and antibacterial peptides. A series of innovative research results have been achieved in aspects such as the biodegradation mechanism of new marine pollutants, the biosynthesis and regulatory mechanism of energy substances, the driving factors and mechanisms of carbon sinks in coastal wetlands, the extraction, expression, purification, efficacy evaluation, structure-activity relationship and industrial application of bioactive proteins and polypeptides.
Teaching and Scientific Research Achievements
(1) Representative Projects:
National Natural Science Foundation of China: Research on the Key Hydrogen Production Genes and Metabolic Pathways of Acid-Resistant High-Efficiency Hydrogen-Producing Bacterium Pannonibacter phragmitetus BH18 (41606157), Liu Hongyan, Principal Investigator
National Natural Science Foundation of China: Research on the Structure of Human ASXL2 and ASXL2-BAP1 Complex and Its Function in Regulating Histone Epigenetic Modifications (31900861), Dong Chunming, Principal Investigator
Key Project of Tianjin Natural Science Foundation: Preparation of Comprehensive Oil Spill Bioremediation Agents and Research on Key Ecological Restoration Technologies for Beach Oil Pollution (18JCZDJC10060), Song Donghui, Principal Investigator
Enterprise-Commissioned Project: Construction, Expression, and Purification of Recombinant Human Collagen, Plant Insulin Aglycin and Vglycin Strains, and Performance Research, Dong Chunming, Principal Investigator, 1.6 million yuan.
Enterprise-Commissioned Project: Research and Development, Testing of New Scientific Reagents and Reagent Kits, Dong Chunming, Principal Investigator, 1.35 million yuan
(2) Representative Publications:
Yuru Yang, Xionge Li, Xinyi Li, Donghui Song*. Quantitative assessment, molecular docking and novel metabolic pathways reveal the interaction mechanisms between norfloxacin biodegradation and environmental implications. Journal of Hazardous Materials, 472 (2024) 134521(CAS Ranking System,Tier 1, 2024 IF 12.2)
Xionge Li, Guangbi Li, Jiaxin Wang, Donghui Song*. Elucidating polyethylene microplastic degradation mechanisms and metabolic pathways via iron-enhanced microbiota dynamics in marine sediments. Journal of Hazardous Materials, 466 (2024) 133655. (CAS Ranking System,Tier 1,2024 IF 12.2)
Ao Wang, Wenxian Fu, Yu Feng, Zhimin Liu, Donghui Song*. Synergetic effects of microbial-phytoremediation reshape microbial communities and improve degradation of petroleum contaminants. Journal of Hazardous Materials, 2022,429,128396. (CAS Ranking System,Tier 1,2022 IF 13.6)
Zhang S, Zhang X, Yuan Y, Li K, Liu H Y*. Renewable biohydrogen production from Clostridium sp. LQ25 using different forms of ferric as electron acceptor. Science of the Total Environment. 2023,855,158911–158917. (CAS Ranking System,Tier 1,2023 IF 9.8)
Chunming Dong, Lijun Xu, Weitao Lu, Mengru Li, Rui Zhang, Yanyan Sun,Jian Liu, Xinlei Chu. Antibacterial peptide PMAP-37(F34-R), expressed in Pichia pastoris, is effective against pathogenic bacteria and preserves plums. Microbial Cell Factories. 2023,22 (1): 164. (CAS Ranking System,Tier 2,IF 6.4)
(3)Awards and Honors:
National Second Postdoctoral Innovation and Entrepreneurship Competition Award, Dong Chunming, 2023
Tianjin Higher Education Institution's Course Ideological and Political Education Demonstration Course Teaching Team (Liu Hongyan, Song Donghui, Dong Chunming), 2021
Tianjin Higher Education Institution's Course Ideological and Political Education Demonstration Course Teaching Master, Liu Hongyan, 2021
Tianjin First-Class Course "Biochemistry", Liu Hongyan (Principal), 2021
The team has guided 6 national-level undergraduate innovation and entrepreneurship projects, and 5 Tianjin-level undergraduate innovation and entrepreneurship projects, 2017-2023.
(4) Textbooks and monographs:
Chinese Light Industry "Thirteenth Five-Year Plan" Textbook "Biochemistry Checklist", Chemical Industry Press, 2021
Higher Education Institution Bioengineering Specialty Textbook "Biochemistry" (Second Edition), China Light Industry Press, 2021
General Higher Education Institution Planning Textbook "Marine Biology", Tianjin Science and Technology Press, 2018
General Higher Education Institution "Eleventh Five-Year Plan" National Planning Textbook "Bioinformatics", China Agricultural Press, 2006.
(5) China National Invention Patents Granted:
Dong Chunming, et al. A recombinant antimicrobial peptide PMAP-37, its preparation method and application, ZL202211236277.5
Liu Hongyan, et al. A strain of heterotrophic iron-reducing bacteria coupled with hydrogen production, ZL201910249017.3
Liu Hongyan, et al. Method for preparing biogenic magnetite using heterotrophic iron-reducing bacteria to remove heavy metal chromium, ZL201910066297.4
Song Donghui, et al. Microalgal sulfated composite polysaccharides, their preparation method and application, ZL201710673111.2
Liu Hongyan, et al. A hydrogen-producing bacterium, ZL201711126954.7